RESEARCH STUDIES AND CLINICAL TRIALS

Patient Recruitment for Studies Conducted by the NIMH, NIH:  We conduct a large number of research studies with patients who have mental health disorders. Our studies are performed at the NIH Clinical Center (CC), a hospital dedicated to the highest quality research. The NIH CC (picture shown on the right) is located in Bethesda, Maryland, near Washington, D.C.  We want to provide you with information about our research and about your disease to help you decide whether to volunteer for participation in one of our studies. If you qualify for a study, then study-related evaluation, treatment and, in some cases, transportation to NIH are provided without cost to you or your health plan.

Clinical Trials.gov – Registry of federally and privately supported clinical trials conducted in the United States and around the world. Gives you information about a trial’s purpose, who may participate, locations, and phone numbers for more details: http://clinicaltrials.gov/ Behaviors and Mental Disorders[CONDITION-BROWSE-BRANCH] | Open Studies | “Depression” | United States, Massachusetts | NIH, U.S. Fed

Clinical Connection, a source for timely clinical trials information, listings, and notifications.
http://clinicalconnection.com/

The Schizophrenia Research Forum website—a virtual community for science about schizophrenia and related disorders. Our Mission is to help researchers in their quest for causes, improved treatments, and better understanding of schizophrenia. http://www.schizophreniaforum.org/

Search Clinical Trials is an easy way to find a clinical trial that may be right for you.

Read A Participant’s Guide to Mental Health Clinical Research Online

or download the guide nimh-participants-guide (PDF)

Go to PubMED – An electronic search engine of scientific articles published in thousands of journals across the world. It is hosted by the National Library of Medicine at the National Institutes of Health

Local Research Studies in Progress:

Depression Studies

ActiveMed Practices & Research is currently enrolling the following studies.docx (Word)

Study of Depression in Romantic Relationships – U Illinois Urbana-Champaign (Word)

Project ADAPT and Project STAR are looking for adolescents between the ages of 13 and 18 yrs (Word)

University of New England RateADrug Depression Feedback survey (Word)

Drug Free Treatment for Depression in Teens and Young Adults in Rhode Island and Cambridge (PDF)

Mood Memos is a University of Melbourne study exploring a method of preventing depression through the internet. The study is targeted to people experiencing some depression symptoms who are not yet too severe, with the aim of averting depression or relapse (Word)

Mood and Menopause Study at UMass (PDF)

 

Bipolar Depression Studies

6-week research study that looks at sleep disturbance in individuals with bipolar disorder (Word)

ActiveMed Practices & Research is currently enrolling the following studies.docx (Word)

B-SNIP Study at MMHC: Families Needed for Bipolar/Schizophrenia/Schizoaffective Study (Word)

Bipolar Disorder study for participants ages 12 to 17 years and generally healthy (Word)

Bipolar and Menopause Research Study – UMASS Medical School (Word)

Bipolar Depression Study at St. Elizabeth and McLean Hospital (Word)

The aim of the research is to find out whether factors such as impulsivity and time perspective can predict the onset of bipolar depression and mania. Survery with all materials-R überarbeitet

The Evaluation of Lamictal as an Add-On Treatment for Bipolar I Disorder in Children and Adolescents, 10 to 17 Years of Age (PDF)

Have you ever been diagnosed with Bipolar Disorder or mania? Do you have a 3 to 5 year-old child? Mass General Study (PDF)

 

 

Schizophrenia Studies

The NIHM Genetic Study of Schizophrenia. Individuals 18 years old or older diagnosed with schizophrenia or schizo-affective disorder (depressed type) may be able to participate in a genetic study that looks for genes in families. In order for family members to participate, the person with schizophrenia must be willing and able to participate. Eligible family members participate in an interview and contribute a sample of blood for genetic analysis. Individuals with schizophrenia, and if possible, their siblings, may qualify to participate in this study. There is no change in medication involved. The study involves simple cognitive tests and some MRI scans (no radiation). All testing is completed free of charge and there is compensation for each family member’s participation in the study. Travel and lodging assistance is also available. Scientists believe that the identification of susceptibility genes is key to understanding the molecular pathways of this disease so that better treatments and preventive methods can be developed in the future. To find out more, please call 301-435-8970 (1-888-674-6464) or email schizophrenia@mail.nih.gov. For more information on research conducted by the National Institute of Mental Health in Bethesda, MD click here:  Read

 

Lurasidone and Cognitive Enhancement Study at MMHC – Interested in new treatments of schizophrenia? (Word)

Schizophrenia Trial for participants ages 12 – 17 years and generally healthy (Word)

NIMH RAISE (Recovery After an Initial Schizophrenia Episode) research project is now actively recruiting participants (Word)

Prevatatin and Schizophrenia Research Study at Freedom Trail Clinic, MGH Schizophrenia Research Program (Word)

Do you have a close relative (parent, sibling, child) who has schizophrenia or schizoaffective disorder (Word)

Schizophrenia Study at St. Elizabeth’s Hospital (Word)

SearchLyte Study on Schizophrenia (Word)

Schizophrenia Program at the Massachusetts General Hospital – Freedom Trail Clinic is conducting a research trial to test the effectiveness of the vitamins Folate and B12 for treating symptoms of schizophrenia (PDF)

Intranasal Insulin Treatment Study at MGH in Patients with Schizophrenia (PDF)

Schizophrenia Program at the Massachusetts General Hospital – Freedom Trail Clinic is conducting a research trial to assess whether Geodon dose escalation (meaning a dose of Geodon higher than is typically used) improves symptoms of schizophrenia compared to continued standard treatment (PDF)

Research Study – Harvard University Social Neuroscience and Psychopathology Lab Have you been diagnosed with Schizophrenia or Schizoaffective disorder? (Word)

Help Participate in a Research Study Comparing the Brains of People With and Without a Family History of Schizophrenia (Word)

Biological Predictors of Psychosis Susceptibility among Adolescent Cannabis Users” Harvard Medical School(Word)

Telmisartan as an Adjunctive Treatment for Metabolic Problems in Patients with Schizophrenia Research Study – Freedom Trail Clinic, MGH Schizophrenia Research Program (Word)

 

OCD Studies

A research study is now enrolling for those who still need help controlling their OCD symptoms. This particular study is looking for people who are still experiencing OCD symptoms despite taking Luvox, Prozac, Paxil, or Zoloft. OCD Clinical Trial News Release (PDF)

Have Obsessive Compulsive Disorder? Interested in learning more? Willing to consider some brain scans (MRI? PET?) or a 14-week medication study? For more info click on this OCD Research Study or Clinical Trial (PDF)  http://psychiatry.yale.edu/ocd/participate/participate.aspx

Other

Are you 18 years or older and experience thoughts or feelings related to suicide?

Understanding the experiences of individuals with serious mental illness I am a graduate student in Clinical Psychology at Bowling Green State University in Ohio. My dissertation project involves better understanding the experiences of individuals with serious mental illness. I am interested in learning more about how people recover from mental health problems and about the losses they experience. Participation in this study involves completing an online questionnaire at your convenience. I estimate that it will take you no longer than 30-45 minutes to complete this survey. If you have been diagnosed with a serious mental illness such as schizophrenia, schizoaffective disorder, bipolar disorder, or major depression, please consider participating in this important study. Contact Jaclyn Leith at jleith@bgsu.edu or at 419-372-4596 in order to express your interest in participating and gain access to the online survey link. For your participation in this study, you will be given a $5 gift card from your choice of one of two major retailers (Target or Amazon.com).

Families Needed for Research Study and the Parent has a Diagnosis of Schizophrenia or Schizoaffective Disorder (PDF)

UMass Medical School’s Center for Health Policy and Research is conducting a study to understand the types of health care services people with disabilities need in order to work or return to work. (PDF)

Internet Education & Social Support Research Study For Mother’s Diagnosed With A Mental Illness (PDF)

Project Implicit Mental Health: learn about the measurement of thoughts about self-harm, anxiety, depression, and other factors that may exist outside your conscious awareness or control.

An internet parenting education and research study (PDF) online parenting education and support group, part of a national research study testing the effectiveness of such a program for mothers with a psychiatric disability

Would you like to contribute to exciting research about hearing voices, as well as have the chance to win Amazon vouchers? A research group based at the University of Surrey in the UK want to find out more about the experiences of people who hear voices. The research group want to know what is most important to help people recover, and build a satisfying life. They hope to improve the treatments offered to people who hear voices, by showing what is most important to voice hearers.  You can visit their website today at www.fahs.surrey.ac.uk/survey/voices to find out more. They will ask you to answer some questions, which should take roughly 25 minutes. To thank you for your time, they will enter those who take part into a raffle to win Amazon vouchers worth up to $75! Please contact the researchers Alison Holt (a.holt@surrey.ac.uk) or Esther Clarke (e.clarke@surrey.ac.uk) for any further information.

NAPLS Study at MMHC- Are you concerned about your child’s mental health (Word)

The Child and Adolescent NeuroDevelopment Initiative (CANDI) conducts on-going research in early-onset bipolar disorder, psychotic disorders, and autism spectrum disorders (Word)

Study of families of mental health consumers and their experiences with law enforecement BU Study (Word)

Research Study – Harvard University Social Neuroscience and Psychopathology Lab Ages 15 -30 (Word)

Research Study – children ages 8-11 – how the brain processes social situations and how this relates to children’s experiences of the world around them and their social relationships (Word)

Participants needed for a research study at the Boston University Center for Psychiatric Rehabilitation is conducting a research study on how adults with psychiatric conditions view work BU Psych Rehab Work Research Study (PDF)

Study of Housing in the Lives of Young Adults with Mental Health Conditions (PDF)

American Foundation for Suicide Prevention (AFSP): Survivor Research – Online Study of Grief-Related Experiences. Complicated Grief Study Seeks Participants in Boston

Teens Needed for Research Study on Physical Activity Choices (Word) The Eunice Kennedy Shriver Center at the University of Massachusetts Medical School in Waltham, MA